Life and Health

Life and Health - Transdisciplinary Research Area (TRA) University of Bonn

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Life exists in complex structures, from the smallest molecules that interact with each other to the interplay of various organisms in ecological systems. Understanding the complexity of life is therefore one of the most fascinating research topics. If researchers decipher the mechanisms underlying life, this will provide the basis for a better understanding of diseases and the development of new therapies. In a lively research environment and together with the Cluster of Excellence "Immunosensation2", the Transdisciplinary Research Area "Life and Health" of the University of Bonn focuses on comprehending life - from the level of the tiniest particles to the interaction of complex systems with the environment. One of the main objectives is the development of new strategies to improve and maintain health.

About the TRA

Find out more about our objectives, TRA organization and team.

Research 

More about our research profile, topics and TRA projects.

Offers

Find out more about research support and events organized by the TRA Life and Health.

Network

More about our partners for young scientists, research an
and transfer.

Organoid Club

The "Bonn Organoid Club" is a forum for interested researchers to exchange expertise and reagents on organoid models in biomedical research.
Next talk: 11.01.2022

Image: Tim Kempchen

Seminars and events

An overview of seminars and events in the thematic area of TRA Life and Health can be found on the website of the Bonner Forum Biomedizin (BFB).

Become member

As TRA member, you will have access to TRA funding and opportunities for networking beyond the borders of your own discipline.

Contact

Avatar Brömer

Dr. Meike Brömer

TRA manager | Strategic Development and Quality Assurance Unit

+49 1511 6933013

News
Hostile takeover in the cell

Mitochondria are known as energy suppliers for our cells, but they also play an important role in the defense against pathogens. They can initiate immune responses, and deprive pathogens of the nutrients they need to grow. A research team led the Max Planck Institute for Biology of Ageing in Cologne has now shown that pathogens can turn off mitochondrial defense mechanisms by hijacking a normal cellular response to stress. Scientists from the University of Bonn were also involved in the study, which was published in the journal Science.

Alzheimer’s research: Inflammatory markers are conspicuous at an early stage

Bonn/Germany, January 12, 2022. Long before the onset of dementia, there is evidence for increased activity of the brain’s immune system. Researchers from DZNE and the University of Bonn come to this conclusion based on a study of more than 1,000 older adults. To this end, various proteins were measured in the cerebrospinal fluid: They served as so-called biomarkers that indicate inflammatory processes of the nervous system. As it turned out, some of these molecules seem to be part of a damage control program of the immune system, which could be useful for the development of new drugs. The study results have been published in the scientific journal “Neuron”.

Antiepileptic drugs with a light switch

Dr. Michael Wenzel from the Department of Epileptology at the University Hospital Bonn has received a coveted Starting Grant from the European Research Council (ERC). With the associated funding of 1.5 million euros for the next five years, the neurologist wants to study novel light-activated drugs with antiepileptic effects investigating how they can help against hard-to-treat epilepsies.

Stem cells organize themselves into embryoid

Researchers at the University of Bonn have developed a method to generate embryo-like cell complexes from the stem cells of mice. The method provides new insights into embryonic development. In the medium term, it might also be suitable for developing tests for substances that could be harmful to fertility. The study is published in the prestigious journal Nature Communications.

Six Transdiciplinary Research Areas of the  University of Bonn

Six TRAs: the research profile of the University of Bonn 

TRA Mathematics, Modelling and Simulation of Complex Systems

TRA Building Blocks of Matter and Fundamental Interactions

TRA Individuals, Institutions and Societies

TRA Past Worlds and Modern Questions. Cultures Across Time and Space

TRA Innovation and Technology for Sustainable Futures

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