Research and Study at the University of Excellence in Bonn

Chemokines are signalling proteins that orchestrate the interaction of immune cells against pathogens and tumours. To understand this complex network, various techniques have been developed to identify chemokine-producing cells. However, it has not yet been possible to determine which cells react to these chemokines. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have developed a new class of genetically modified mice that enables the simultaneous identification of chemokine producers and sensors. Using the chemokine Ccl3 as a “proof of principle”, they discovered that its function in the immune defence against viruses is different than had been previously assumed. Their results have now been published in the "Journal of Experimental Medicine".

Uveitis is a rare inflammatory eye disease. Posterior and panuveitis in particular are associated with a poor prognosis and a protracted course of the disease. Diagnosis and monitoring can be challenging for healthcare professionals. Fundus autofluorescence (FAF) is a fast and non-invasive imaging technique that supports this. Researchers from the University Hospital Bonn and the University of Bonn, together with experts from Berlin, Münster and Mannheim, have drafted a review on how FAF can facilitate the diagnosis and monitoring of posterior uveitis and panuveitis. The results have now been published in the journal "Biomolecules".

The University of Bonn’s Team NimbRo was the top scoring team in the @Home league for household robots at the RoboCup German Open, held in Kassel from April 18-20. Developed by the Autonomous Intelligent Systems working group at the Institute of Computer Science, NimbRo’s lifelike soccer-playing robots had the best final-round test results, according to the judges panel. The robots are able to navigate around on their own, grasp and place objects and interact with people via voice dialogue technology. 

The Russian invasion of Ukraine and Hamas’ attack on Israel are just two of the many conflicts that continue to shake the world. War would just seem to be part of human nature. Although making this observation 230 years ago, the polymath Immanuel Kant (1724-1804) then proceeded to formulate a 100-page blueprint for perpetual peace. Professor Rainer Schäfer from the Digital Kant Center NRW in Bonn discusses the practicality of Kant’s concept and its relevance for the 21st century.