Research and Teaching at the University of Bonn

An international team of researchers led by the University of Bonn has identified the cause of a rare, severe muscle disease. According to these findings, a single spontaneously occurring mutation results in the muscle cells no longer being able to correctly break down defective proteins. As a result, the cells perish. The condition causes severe heart failure in children, accompanied by skeletal and respiratory muscle damage. Those affected rarely live beyond the age of 20. The study also highlights experimental approaches for potential treatment. Whether this hope will be fulfilled, however, will only become clear in a few years. The results are published in the journal Nature Communications.

How do elites emerge? Do they exercise power independently or only 'by order'? How is domination transmitted and perpetuated? These and many other questions will be transculturally addressed by researchers from June 17 to 19 during the digital conference "Rulers and Elites between Symbiosis and Antagonism. Communicating in Premodern Hegemonic Structures". All those interested are invited to attend. The free event will be held via the Zoom conference system.

The so-called Plexin-A1 gene seems to play a more extensive role in brain development than previously assumed. This is shown by a current study led by the University Hospital Bonn and the Institute of Anatomy of the University of Bonn with more than 60 international partners. The gene is also interesting for another reason: Its mutations are inherited either dominantly or recessively, depending on which part of the gene is affected. The results of the study are now published in the journal "Genetics in Medicine".

Artificial intelligence (AI) can be an important tool for sustainable development to minimize energy usage in large factories or to predict natural disasters before they happen. However, these uses can also have a social and ethical downside. For example, training and tuning AI models produces carbon emissions that harm the environment. Or there are power asymmetries between people when not everyone gets access to the technology. At the world's first conference on the sustainability of artificial intelligence, researchers will discuss environmental, social and economic costs of designing, developing, and using AI from June 15 to 17. The virtual conference is launched by AI ethicist Prof. Aimee van Wynsberghe, Humboldt Professor at the University of Bonn. The conference is supported by the Alexander von Humboldt Foundation and the Institute for Science and Ethics at the University of Bonn.