Natalija Novak
Prof. Dr. Natalija Novak
  • Klinik für Dermatologie und Allergologie, Universitätsklinikum Bonn
Research topics
  • atopic dermatitis
  • IgE receptor
Research Expertise: Pathophysiology of atopic dermatitis including genetic changes, regulation of the surface expression of the high affinity receptor for IgE on dendritic cells, role of IgE receptor bearing Langerhans cells and inflammatory dendritic epidermal cells, predictive factors for atopy in cord-blood, development and characterization of new therapeutic strategies for allergic diseases and atopic dermatitis, role of dendritic cells in the oral and nasal mucosa, immunmechanisms of allergen-specific immunotherapy role of tyrosine kinase receptors in mastocytosis.
Selected publications

Novak N, Tepel C, Koch S, Brix K, Bieber T, Kraft S. Evidence for a differential expression of FcRI- chain in dendritic cells of atopic and non-atopic donors. J Clin Invest 2003, 28: 184-187.

Peng WM, Maintz L, Allam JP, Raap U, Gütgemann I, Kirfel J, Wardelmann E, Perner S, Zhao W, Fimmers R, Walgenbach K, Oldenburg J, Schwartz LB, Novak N. Increased circulating levels of neurotrophins and elevated expression of their high-affinity receptors on skin and gut mast cells in mastocytosis. Blood 2013, 122(: 1779-178.

Yu CR, Peng WM, Schlee M, Barchet W, Eis-Hübinger AM, Kolanus W, Geyer M,. Schmitt S, Steinhagen F, Oldenburg J, Novak N. SOCS1 and SOCS3 target IRF7 defradation to supress TLR7-mediated type I IFN production of human plasmacytoid dendritic cells. J Immunol 2018, 200: 4024-4035.

Peng W, Kwiek B, Yu C, Garbi N, Allam JP, Oldenburg J, Novak N. Infiltration and Clustering of Major Histocompatibility Complex II+ Antigen-Presenting Cells in the Skin of Patients with Atopic Dermatitis. J Invest Dermatol. 2021, epubmed ahead of print

Natalija Novak
Prof. Dr. Natalija Novak
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