© Uni Bonn
Prof. Dr. Heinz Beck
TRA Speaker
TRA Speaker
Affiliations
- Institute for Experimental Epileptology and Cognition Research
Research topics
- neuronal circuits
- behavior
- neurological disorders
We have an overarching research interest in understanding the function of recurring motifs in the intricate brain circuitry, and how these give rise to complex functions in the intact brain. On the level of single neurons, we are interested in how the many thousands of excitatory inputs are integrated at neuronal dendrites, and how they interact with inhibitory and modulatory synaptic inputs. Our group also has a strong track record investigating basic-mechanisms of epilepsy in animal models and tissue obtained from epilepsy surgery, and we are examining the network correlates of epilepsy, as well as the mechanisms of CNS drug actions on the network level, using the techniques described.
Selected publications
Masala, N., Pofahl, M., Haubrich A.N., Nikbakht, N., Bohmbach, K., Henneberger, C., Golcuk, K., Kelly, T., Beck, H. (2022) Degraded dendritic input feature detection underlies spatial memory deficits in epilepsy. Brain, doi: 10.1093/brain/awac455.
Braganza, O., Beck, H. (2018) The circuit motif as conceptual tool for multilevel neuroscience. Trends in Neurosciences, 41(3):128-136.
Pabst, M., Braganza, O., Dannenberg, H., Rosen, J., van Loo, K., Deisseroth, K., Schoch, S., Becker, A., Beck, H. (2016) Astrocytic intermediaries of septohippocampal cholinergic transmission. Neuron, 90, 1-13.
Krüppel, R., Remy, S., Beck, H. (2011) Dendritic integration in hippocampal dentate granule cells. Neuron, 71:512-528.
© Uni Bonn
Prof. Dr. Heinz Beck
TRA Speaker
TRA Speaker