Dirk Menche
Prof. Dr. Dirk Menche
  • Kekulé-Institut für Organische Chemie und Biochemie
Research topics
  • chemistry of natural products
Research interests of our group are centered around complex natural products chemistry, ranging from advanced NMR studies, method development, multi-step total synthesis to Structure-Activity-Studies and Medicinal Chemistry. Many of the underlying research questions are adressed in cooperative ventures with various biological partners.
Selected publications

Göricke B, Bieber MF, Mohr KE, Menche D. (2019) Stereochemical Determination of Tuscolid/Tuscorons and Total Synthesis of Tuscoron D and E: Insights into the Tuscolid/Tuscoron Rearrangement. Angew. Chem. Int. Ed. 58:13019-13023.

Herkommer D, Thiede S, Wosniok PR, Dreisigacker S, Tian M, Debnar T, Irschik H, Menche D. (2015) Stereochemical Determination of the Leupyrrins and Total Synthesis of Leupyrrin A1. J. Am. Chem. Soc. 137:4086-4089.

Dieckmann M, Kretschmer M, Li P, Rudolph S, Herkommer D, Menche D. (2012) Total Synthesis of Rhizopodin. Angew. Chem. Int. Ed. 51:5667-5670.

Essig S, Bretzke S, Müller R, Menche D. (2012) Full Stereochemical Determination of Ajudazols A and B by Bioinformatics Gene Cluster Analysis and Total Synthesis of Ajudazol. J. Am. Chem. Soc. 134:19362-19365.

Dirk Menche
Prof. Dr. Dirk Menche
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