Sergio Castro-Gomez
Dr. Dr. Sergio Castro-Gomez
Zugehörigkeiten
  • Zentrum für Neurologie
  • Institut für Physiologie II
Forschungsschwerpunkte
  • neuroinflammation
  • neurodegeneration
  • neuroimmunology
  • cognition
Our goal is to study, educate and investigate on molecular and cellular mediators of acute and chronic neuroinflammation in different neurological disorders using innovative experimental models for neurodegeneration after brain injury and in the context of neurodegenerative diseases such as Alzheimer’s disease and other tauopathies.
Ausgewählte Publikationen

NLRP3 inhibition maintains microglia architecture and enhances behavioral recovery after traumatic brain injury. Castro-Gomez S* # , Vieira-Saecker A, Muñoz-Manco JI, Tao L, Kulińska I, Weiss FD, Meissner F, Schwartz A, Stein V, Latz E, Heneka MT. bioRxiv 2025.06. doi.org/10.1101/2025.06.25.660862 -

ASC contributes to sustained glial reactivity and mild cognitive impairment after closed-head injury. Li T, Castro-Gomez S* # , Botella Lucena P, Vieira-Saecker A, Schwartz A, Deng Y, Ding Y, Stein V, Latz E, Heneka MT bioRxiv 2025.06. doi.org/10.1101/2025.06.19.660521 *Co-first author # Co-Corresponding author

Innate immune activation in neurodegenerative diseases. Castro-Gomez S, Heneka MT. Immunity. 2024 Apr 9;57(4):790-814. doi: 10.1016/j.immuni.2024.03.010.

Teaching an old dog new tricks: serum troponin T as a biomarker in amyotrophic lateral sclerosis. Castro-Gomez S, Radermacher B, Tacik P, Mirandola SR, Heneka MT, Weydt P. Brain Commun. 2021 Nov 17;3(4):fcab274. doi: 10.1093/braincomms/fcab274.

Arc/Arg3.1 mediates a critical period for spatial learning and hippocampal networks. Gao X*, Castro-Gomez S*, Grendel J*, Graf S, Süsens U, Binkle L, Mensching D, Isbrandt D, Kuhl D, Ohana O.Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):12531-12536. doi: 10.1073/pnas.1810125115. Epub 2018 Nov 15.PMID: 30442670 *Co-first author # Co-Corresponding author

Sergio Castro-Gomez
Dr. Dr. Sergio Castro-Gomez
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