© Boas Pucker
Prof. Dr. Boas Pucker
Zugehörigkeiten
- Institut für Zelluläre & Molekulare Botanik (IZMB)
Forschungsschwerpunkte
- biosynthesis pathway discovery
- metabolic engineering
- synthetic biology
Our research focuses on plant biotechnology and applied bioinformatics, using genomics and transcriptomics to explore biosynthetic pathways in plants. We transfer plant biosynthetic genes into microorganisms to produce valuable plant-derived compounds. While flavonoid biosynthesis is our core model, we also investigate pathways with biomedical significance, including camptothecin and withanolides. We also collaborate with group from medical sciences by conducing computational analyses on animal or viral data sets.
Ausgewählte Publikationen
Gruenig N, Pucker B. CoExpPhylo – A novel pipeline for biosynthesis gene discovery. bioRxiv. 2025;2025.04.03.647051. doi:10.1101/2025.04.03.647051
Rempel A, Choudhary N, Pucker B. KIPEs3: Automatic annotation of biosynthesis pathways. PLoS One. 2023;18(11):e0294342. doi:10.1371/journal.pone.0294342
Natarajan S, Pucker B, Srivastava S. Genomic and transcriptomic analysis of camptothecin producing novel fungal endophyte: Alternaria burnsii NCIM 1409. Sci Rep. 2023;13:14614. doi:10.1038/s41598-023-41738-6
Hakim SE, Choudhary N, Malhotra K, Peng J, Arafa A, Bültemeier A, et al. Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis. bioRxiv. 2024. doi:10.1101/2024.09.27.614867
© Boas Pucker
Prof. Dr. Boas Pucker