Aleksandra Pandyra
Prof. Dr. Aleksandra Pandyra
Zugehörigkeiten
  • Institut für klinische Chemie und klinische Pharmakologie, Universitätsklinikum Bonn
Forschungsschwerpunkte
  • onco-immunology
  • novel therapeutics
  • infection
Our mission is to advance cancer and viral infection treatment by investigating anti-tumoral and anti-viral immune responses using innovative in vivo models. We focus especially on poorly immunogenic tumors, such as childhood leukemia, to uncover new immune-boosting therapies.
Ausgewählte Publikationen

1) Stachura P, Lu Z, Kronberg RM, Xu HC, Liu W, Tu JW, Schaal K, Kameri E, Picard D, von Karstedt S, Fischer U, Bhatia S, Lang PA, Borkhardt A, Pandyra AA. Deep transfer learning approach for automated cell death classification reveals novel ferroptosis-inducing agents in subsets of B-ALL. Cell Death Dis. 2025 May 18;16(1):396. 


2) Lu Z, Stencel O, Liu W, Vasileiou E, Xu HC, Pandey P, Stachura P, Elwy A, Tsombal A, Mai AS, Auer F, Morcos MNF, Seidl M, Koziel S, Bruch PM, Dietrich S, Elitzur S, Hartmann G, Lang KS, Janssen S, Fischer U, Bhatia S, Lang PA, Borkhardt A, Hauer J, Pandyra AA. Immune training enhances anti-viral responses and improves outcomes in Pax5-/+ mice susceptible to chronic infection. EMBO Mol Med. 2025 Apr;17(4):696-721. 


3) Stachura P, Liu W, Xu HC, Wlodarczyk A, Stencel O, Pandey P, Vogt M, Bhatia S, Picard D, Remke M, Lang KS, Häussinger D, Homey B, Lang PA, Borkhardt A, Pandyra AA. Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors. Mol Cancer. 2023 Aug 15;22(1):136. 


4) Liu W, Stachura P, Xu HC, Váraljai R, Shinde P, Ganesh NU, Mack M, Van Lierop A, Huang A, Sundaram B, Lang KS, Picard D, Fischer U, Remke M, Homey B, Roesch A, Häussinger D, Lang PA, Borkhardt A, Pandyra AA. BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment. Cancer Res. 2022 Jan 15;82(2):264-277.

Aleksandra Pandyra
Prof. Dr. Aleksandra Pandyra
Wird geladen