Organoid Club - Participating Labs

Dirk Baumjohann

Type of Organoids: Human adenoid/tonsil-based immune organoids

Methods: Immune organoids
Research Topics: Immunology, drug testing

Oliver Brüstle

Type of Organoids: Cortical organoids, myelinoids, human, iPSC derived

Methods: Toxicology screening, disease modeling, genetic engineering, fluorescence microscopy, multiomics
Research Topics: Drug/Toxicology screening, Disease modeling

Volker Busskamp

Type of Organoids: Retinal Organoids, Neuromuscular Junction Organoids, Printed neuronal circuits

Methods: Forward programming of stem cell, vascularization of organoids, electrophysiology, microfluidics, optogenetics
Research Topics: Visual Neuroscience, Bioengineering, Vision Restoration

Rabiul Hosen

Yongguo Li

Type of Organoids: Thermogenic fat organoids (mouse, human)

Methods: Multiomics, vascularization, genetic modifying, snRNA-seq, organ-on-a-chip
Research Topics: Metabolism, biogenegetics, drug screening, tissue development, cellular crosstalk

Veronika Lukacs-Kornek

Type of Organoids: Lymph node 3D culture, stromal cells cultures, multicellular spheroid

Methods: Immune organoids
Research Topics: Stroma-T cell interaction, stroma-tumor intercation

Elvira Mass

Type of Organoids: Cerebral organoids, human iPSC-derived

Methods: Immune-competent brain organoids, transcriptomics, metabolic profiling, fluorescence microscopy
Research Topics: Environmental factors, neurodevelopment, neuroinflammation

Alexander Pfeifer

Type of Organoids: Human iPSC-derived brown adipose organoids

Methods: Live imaging, whole-mount fluorescence imaging, vascularization
Research Topics: Thermogenesis, tissue modeling, cell-cell crosstalk 

Elena Reckzeh

Type of Organoids: Gut, colorectal cancer (human, mouse)

Methods: Drug Screening, Assay development, Transwells, Fluidics, Organoid reporter Lines (CRISPaint)
Research Topics: Metabolism, nutritent uptake, personalized therapy

Manuel Ritter

Type of Organoids: Lung, lymphatic vessels, bronchialveloar (human, mouse)

Methods: Establishment of helminth organoid models
Research Topics: Helminths, drug screening

Carmen Ruiz de Almodóvar

Type of Organoids: Blood vessels, neurovascular unit

Methods: 3D blood vessels system, BBB models, neurovascular unit on a chip
Research Topics: Neurovascular biology, neurodevelopment, neuroimmunology

Florian I. Schmidt

Type of Organoids: Intestinal epithelial organoids (human, mouse), skin explants (human)

Methods: Genetic engineering, infections with DNA and RNA viruses, fluorescence mircoscopy, nanobodies
Research Topics: Innate immune responses, virus infections

Ana Ivonne Vazquez-Armendariz

Type of Organoids: Lung, white adipose tissue (human, mouse)

Methods: Disease modeling, immune-competent organoids, vascularization of organoids
Research Topics: Immune-epithelial cell crosstalk, metaflammation

Dagmar Wachten

Type of Organoids: White adipose tissue, kidney (human, mouse)

Methods: Optogenetics to manipulate cellular signaling
Research Topics: Primary cilia-dependent cell-cell communication in tissue niches (immune cells - non-immune cells)

Heike Weighardt/Irmgard Förster

Type of Organoids: Adipose tissue organoids (mouse)

Methods: Immune-competent organoids, Fluorescence microscopy, Flow cytometry, Lipidomics
Research Topics: Environmental influence on metabolism, Immune cell-adipocyte crosstalk

Zahra Farzaneh

Type of Organoids: Human iPSC-derived endocardial organoid, cardiac spheroid