17. April 2024

Detecting diseases more precisely with lysosome analysis Detecting diseases more precisely with lysosome analysis

Prototyping grant awarded to team from the Faculty of Medicine

The lysosome is a part of human cells and has been linked to a variety of diseases, including cancer. Proteins derived from lysosomes have a high potential to serve as biomarkers, which allow to detect diseases in the human body. A research team led by Dr. Dominic Winter (Institute of Biochemistry and Molecular Biology and University Hospital Bonn) has developed an innovative assay to analyze these lysosomal proteins and, therefore, to detect potential new biomarkers. With this assay, diseases could be tracked down more efficiently in the future. The project is now being funded with a prototyping grant to further develop the method to commercialization. The grants with a funding amount of up to €50,000 are regularly awarded by the Transfer Center enaCom. Applications for prototype development in 2024 can currently be submitted until 31.05.2024.

Prototyping Grant for Team LysoQuant
Prototyping Grant for Team LysoQuant - Dr. Dominic Winter, Dhriti Arora, Anne Sanner (from left to right) © Anne Sanner / enaCom
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"The innovation of our project is a refined method in which we use mass spectrometry – a method for measuring the mass of molecules – to better investigate the abundance of lysosomal proteins in patient samples. This will ultimately enable us to identify diseases more precisely," says Dr. Dominic Winter, explaining his product idea for the biopharmaceutical market. Lysosomal proteins could serve as potential biomarkers for over 200 different possible diseases. Dr. Winter is working on the project "LysoQuant - Identification of Lysosome-related Biomarkers by Targeted Mass Spectrometry" together with his doctoral students Dhriti Arora and Anne Sanner.

Ongoing funding by the Transfer Center

"The prototyping grants are aimed to promote innovative ideas and their development for the market. Over the past two years, we have supported teams from a range of disciplines - from agricultural or social sciences to medicine," says Sandra Speer, Head of the Transfer Center enaCom.

The projects are closely supported by the Transfer Center's start-up consulting team. The funding is offered by enaCom and financed by the ESC (Excellence Startup Center) individual project "U-Bo-Grow" at the University of Bonn. It is funded by the Ministry of Economic Affairs, Industry, Climate Protection and Energy (MWIKE) of the state of North Rhine-Westphalia. 

Applications for funding for prototype development in 2024 can be submitted by May 31st 2024. Find all information here.

Team LysoQuant
Team LysoQuant - Dr. Dominic Winter, Dhriti Arora, Anne Sanner (from left to right) © Anne Sanner

If you are interested in the funding line, please contact:

Dr. Alexander Küsshauer, Start-Up Advisor

+49 228 73-62026

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