Christian Kurts
Prof. Dr. Christian Kurts
Zugehörigkeiten
  • Institut für Molekulare Medizin und Experimentelle Immunologie
Forschungsschwerpunkte
  • immune tolerance
We are interested in understanding immune-mediated diseases and in strategies to monitor and therapeutically influence the balance between immunity and tolerance. We focus at 3 major topics: 1. Role of dendritic cells in tissue inflammation, especially of the urogenital tract 2. Peripheral immune tolerance against self antigens 3. Role of cytotoxic CD8+ T cells in viral infections and tumor immunity
Ausgewählte Publikationen

Burgdorf S, Kautz A, Böhnert V, Knolle PA, Kurts C. 2007. Distinct antigen uptake and intracellular routing mechanisms in CD4 and CD8 T cell activation. Science, 316: 612-6

Semmling V, Lukacs-Kornek V, Thaiss CA, Quast T, Hochheiser K, Panzer U, Rossjohn J, Cao J, Godfrey DI, Savage P, Knolle PA, Kolanus W, Förster I, Kurts C. 2010. Alternative cross-priming through CCL17-CCR4-mediated CTL attraction towards NKT cell-licensed dendritic cells. Nat Immunol, 11:313-20

Schiwon M, Weisheit C, Franken L, Gutweiler S, Dixit A, Meyer-Schwesinger C, Pohl J, Maurice NJ, Thiebes S, Lorenz K, Quast T, Fuhrmann M, Baumgarten G, Lohse MJ, Opdenakker G, Bernhagen J, Bucala R, Panzer U, Kolanus W, Gröne HJ, Garbi N, Kastenmüller W, Knolle PA, Kurts C*, Engel DR*. 2014. Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium. Cell 156:456–68

Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt S, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. 2020. A high-salt diet compromises the neutrophil response against bacterial infections through hormonal perturbations. Science Transl Med, Epub Mar 25;12(536) doi: 10.1126/scitranslmed.aay3850

Christian Kurts
Prof. Dr. Christian Kurts
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