Understanding How Genes Interact
How do our genes determine our appearance and our susceptibility to disease? This question is central to biomedical research, and today we can sequence thousands of human genomes to identify these genes. However, genes work in complex networks. In a major transdisciplinary collaboration, an international team of geneticists and bioinformaticians set out to create a so-called genetic interaction (GI) map of a human cell. With significant contributions from the Canadian Donnelly Centre, the University of Minnesota, the Hospital for Sick Children in Canada, the University Hospital Bonn, and the University of Bonn, a first draft has now been published in the journal Cell. This draft currently covers about 2.5 percent of all possible gene pairs. 
Why CEOs are getting older
In a new discussion paper, a team of researchers from the Universities of Bonn and Princeton demonstrates that executives in the US are now reaching top positions later than they did two decades ago. This trend towards higher CEO age at appointment is particularly pronounced outside the largest listed firms. The researchers attribute this development to the fact that firms increasingly demand broad knowledge and diverse skills from their CEOs.
Less hunger, more environmental problems?
In sub-Saharan Africa, many people are undernourished or malnourished. A new study by the Universities of Bonn and Ghana shows how rising incomes and urbanization are influencing dietary patterns of local populations. According to this, the wealthier segments in African countries are increasingly eating like people in Western industrialized countries. Although this improves their supply of important nutrients, it also has a greater negative impact on the environment. The study also looks at how this environmental damage can be minimized. It has been published in the journal ‘Sustainable Production and Consumption.’
What AI Actually Does in Diffusion Models
In the search for new drugs, artificial intelligence in the form of diffusion models is being used in drug design. What exactly does AI do in this context? Dr. Andrea Mastropietro and Prof. Dr. Jürgen Bajorath from Life Science Informatics at the University of Bonn and the Lamarr Institute for Machine Learning and Artificial Intelligence have investigated this.
Wird geladen