Tracking down leaks in the blood-brain barrier

In epilepsy research, it has long been assumed that a leaky blood-brain barrier is a cause of inflammation in the brain. Using a novel method, researchers from the University of Bonn an the Bonn University Hospital (UKB) have demonstrated that the barrier between the blood and the central nervous system remains largely intact. The approach of their study provides important insights into the development of epilepsy and could significantly optimize drug development in the pharmaceutical industry. The study results have recently been published in the journal Nature Communications.

Researchers solve a 150-year-old mystery

Aetosaurs had a small head and a crocodile-like body. The land dwellers were up to six meters long and widely distributed geographically. They died out about 204 million years ago, at the end of the Triassic. In Kaltental near Stuttgart, Germany, an assemblage of 24 Aetosaurus ferratus individuals, only between 20 and 82 centimeters long, was discovered in 1877. Since then, scientists have been puzzling over whether they were juveniles or small adults. A team led by Elżbieta M. Teschner from the University of Bonn has now solved the mystery: Bone examination of two specimens shows that they are juveniles. The results have now been published in the Journal of Vertebrate Paleontology.

Mathematician Angkana Rüland joins the University of Bonn

Excellent reinforcement for the University of Bonn: Mathematician Angkana Rüland has accepted the call to a Hausdorff Chair. These are professorships for outstanding scientists at the Cluster of Excellence Hausdorff Center for Mathematics (HCM). The 35-year-old is the second woman to hold this position and is herself an alumna of the University of Bonn. She will take up her position in March of this year.

New compound inhibits influenza virus replication

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza. The team led by Prof. Hiroki Kato from the Institute of Cardiovascular Immunology at the University Hospital Bonn has identified a compound that inhibits the body's own methyltransferase MTr1, thereby limiting the replication of influenza viruses. The compound proved effective in lung tissue preparations and mouse studies and showed synergistic effects with already approved influenza drugs. The study is now published in the journal Science. 

After pandemic break, a delegation visits partner universities and research organizations in Japan

After a long unplanned pandemic break, a delegation from the University of Bonn’s Rectorate and International Office visited four partner universities and several research organizations in Japan and formed new cooperation agreements. The goal of the visit was to reinvigorate the University’s existing partnerships and to prepare the ground for further collaborations in research and teaching. Topics of the exchanges were current developments in the German and Japanese higher education and research landscapes as well as university initiatives for more sustainable futures. 

Two ERC Consolidator Grants for the University of Bonn

Grants from the European Research Council (ERC) go to outstanding researchers and provide funding worth millions. At the University of Bonn, two people are receiving coveted ERC Consolidator Grants: Prof. Dr. Annaliese Mason from the Institute of Crop Sciences and Resource Conservation (INRES) and Prof. Dr. Dennis Lehmkuhl from the Institute of Philosophy.

Meat import ban in Africa hurts local population

The EU regularly exports large quantities of poultry meat to West African countries. These exports have been criticized for harming importing countries in West Africa and exacerbating poverty there. The reason: Cheap imports depress the local price of chicken, making life difficult for local smallholders. Researchers at the Universities of Bonn and Göttingen have now used the example of Ghana to calculate the effects that would result if the country were to significantly increase its import tariffs for poultry meat or even stop imports completely. The result: Prices would indeed rise domestically, but most local households would not benefit. The study has been published in the journal Food Security.

European Football Championship with side effects

The 2020 UEFA European Football Championship, which was played in 2021, had a very different impact on the infection dynamics of the coronavirus pandemic in different participating countries. The extent to which the rates of infection and death from Covid-19 increased depended primarily on the pandemic situation in the country at the start of the championship. This was concluded by physicists in an analysis of epidemiological data. The study involved the Max Planck Institute for Dynamics and Self-Organization in Göttingen, the Max Planck Institute for Physics in Munich, as well as the Universities of Bonn and Göttingen and the PUNCH4NFDI consortium in the German national research data infrastructure NFDI. The study was published in Nature Communications. 

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