Fighting cancer cells with immune cells

The research group led by Dr. Laura Surace at the Institute of Clinical Chemistry and Clinical Pharmacology at the University Hospital Bonn has received funding from the German Cancer Aid through the Max Eder Junior Research Group Program. The program was established to specifically support the research of up-and-coming young oncologists. This is intended to benefit not only the field of oncology, but also the training of the researchers. Surace joins a group of around 30 young scientists who are being supported throughout Germany.

New project to eliminate worm infections in sub-Saharan Africa

Worm infections (helminthiases) affect around 1.5 billion people worldwide, making them one of the most prevalent infections in humans. Parasitic worms (helminths) are often transmitted through insect bites or contaminated soil in areas with limited access to clean water, sanitation, and healthcare. These infections can cause chronic and debilitating health problems, such as lymphatic filariasis, onchocerciasis (river blindness), loiasis (African eye worm), mansonellosis, and trichuriasis (whipworm infection).In the new eWHORM project, coordinated by Prof. Dr. Marc Hübner from the University of Bonn, African and European partners join forces to enable the World Health Organisation’s (WHO) “Road Map for Neglected Tropical Diseases” (NTDs) and reduce the burden of disease associated with worm infections.

Better air due to slurry acidification

Large quantities of excrements are produced in livestock farming. When it is stored in the barn and spread on the fields as fertilizer, ammonia is produced. The gas is harmful to health and also significantly pollutes the environment. A retrofit solution for existing barn systems promises a remedy: A study by the University of Bonn shows that this can reduce ammonia emissions by around 40 percent just inside the barn. It reduces the production of methane, a powerful greenhouse gas, even more significantly. The method could therefore also make an important contribution to the fight against climate change. The results will be published in the Journal of Environmental Management, but are already available online.

Cells refine palm fat into olive oil

For more than 50 years, it has been suspected that fat cells constantly remodel the lipids they store. Researchers at the University of Bonn have now demonstrated this process directly for the first time using culture cells. Among other things, the study shows that the cells quickly eliminate harmful fatty acids. They refine others into molecules that can be used more effectively. In the long term, this turns the components of palm fat into the building blocks of high-quality olive oil, for example. The results have now been published in the journal Nature Metabolism.

New research group on the deformation of structures and infrastructure

Roads, bridges and dams age. How long can such structures still bear the weight? The new research group “Deformation Analysis with Terrestrial Laser Scanner Measurements (TLS-Defo)” at the University of Bonn wants to make a step forward in answering these questions. The German Research Foundation (DFG) will fund the group with around 2.4 million euros over the next four years.

A new look at the power houses of cells

The German Research Foundation (DFG) is establishing a new priority program coordinated by the University of Bonn. Prof. Dr. Thomas Becker from the Institute of Biochemistry and Molecular Biology and his colleagues are focusing their attention on how the power houses of the cell (mitochondria) are integrated into the cellular proteostasis network. Proteostasis stands for the basic cell biological processes such as the folding, transport and degradation of proteins. A deeper insight into the interplay of mitochondria and proteostasis network may contribute to better understanding of neurodegenerative diseases and aging processes. The DFG is funding the supraregional network with around 7.8 million euros for an initial period of three years.

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