Sebastian Zimmer
Prof. Dr. Sebastian Zimmer
TRA Steering Committee
Zugehörigkeiten
  • Medizinische Klinik und Poliklinik II, Universitätsklinikum Bonn
Forschungsschwerpunkte
  • cardiovascular diseases
  • danger signaling pathways
Investigation of danger signaling pathways in the pathogenesis of cardiovascular diseases including atherosclerosis and aortic disease.
Ausgewählte Publikationen

Zimmer S et al. (2016) Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Sci Transl Med 8:333ra50-333ra50.

Niepmann ST, Steffen E, Zietzer A, Adam M, Nordsiek J, Gyamfi-Poku I, Piayda K, Sinning J-M, Baldus S, Kelm M, Nickenig G, Zimmer S, Quast C (2019) Graded murine wire-induced aortic valve stenosis model mimics human functional and morphological disease phenotype. Clin Res Cardiol 368:1005–1010

Asdonk T, Steinmetz M, Krogmann A, Ströcker C, Lahrmann C, Motz I, Paul-Krahe K, Flender A, Schmitz T, Barchet W, Hartmann G, Nickenig G, Zimmer S (2016) MDA-5 activation by cytoplasmic double-stranded RNA impairs endothelial function and aggravates atherosclerosis. J Cell Mol Med 20:1696–1705.

Zimmer S, Steinmetz M, Asdonk T, Motz I, Coch C, Hartmann E, Barchet W, Wassmann S, Hartmann G, Nickenig G (2011) Activation of endothelial toll-like receptor 3 impairs endothelial function. Circ Res 108:1358–1366.

Sebastian Zimmer
Prof. Dr. Sebastian Zimmer
TRA Steering Committee
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