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News
New vulnerability of asthma immune cells discovered
Why do certain immune cells remain permanently active in allergic asthma – even in an environment that should actually damage them? A team from the University Hospital Bonn (UKB) and the University of Bonn has discovered that these cells only survive because they activate a special antioxidant protection mechanism. When this mechanism is blocked, allergic inflammation in mouse models decreases significantly. The results have now been published in the scientific journal Immunity.
Quantum sensors: Highly precise measurements in moving brains
What is happening in the brain during an epileptic seizure? How do nerve cells function after a stroke-induced paralysis? What happens in the heads of those suffering from Parkinson’s disease? Investigating these types of questions has been difficult up to now because patients had to keep still. However, Optical Pumped Magnetoencephalography (OPMEG) is making it possible to also scan the brain while the patient is moving. Prof. Dr. Dominik Bach, Hertz Chair for Artificial Intelligence and Neuroscience at the University of Bonn, is currently setting up this type of research infrastructure on the campus of the University Hospital Bonn (UKB) and will receive funding of almost four million euros over the next three years from the EFRE/JTF program run by the European Union and the state government of North Rhine-Westphalia.
How hunger affects mood
When we are hungry, our mood often drops – a phenomenon colloquially known as “hangry.” A new study by the University Hospital Bonn (UKB), the University of Bonn, and the University Hospital Center Tübingen now shows that this connection is not caused by unconscious metabolic processes. Rather, the decisive factor is that the lack of energy is consciously perceived as hunger – it is this conscious feeling of hunger that leads to a worse mood. The results have now been published in the journal eBioMedicine.
Sustainable pest management would have positive effects across the globe
What would happen if farmers around the globe were to switch over to sustainable pest management? An international study headed by the University of Bonn and ETH Zurich focused on precisely this question. The study is based on assessments provided by more than 500 leading experts from around the world who work in various disciplines from ecology through to economics. Most of those surveyed believe that the consequences of such a transformation would be positive in the long term – even from an economic perspective. However, the main effects of this transformation will vary around the world depending on the region. The results were recently published in the journal Nature Communications.
Microplastics filter inspired by fish
Wastewater from washing machines is considered a major source of microplastics – tiny plastic particles that are suspected of harming human and animal health. Researchers at the University of Bonn now have developed a filter to curb this problem. Their filter was inspired by the gill arch system in fish. In initial tests, the now patent-pending filter was able to remove over 99 percent of plastic fibers from washing machine wastewater. The results now have been published in the journal npj Emerging Contaminants.
A starting point for the development of new pain and cancer drugs
The human P2X4 receptor plays an important role in chronic pain, inflammation and some types of cancer. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have now discovered a mechanism that can inhibit this receptor. The results were recently published in the scientific journal Nature Communications and open up a pathway for the development of new drugs.
GO-Bio Funding: Another Very Strong Showing for Start-Up Projects
The University of Bonn has again succeeded in garnering funding under the GO-Bio initial grant program this year, with as many as six innovative projects attracting 100,000 euros of funding for their conceptual phase. During the one-year funding term, project teams from the University of Bonn and University Hospital Bonn (UKB) will be applying their research findings to develop practical medical and health care solutions. GO-Bio initial is a program launched by the Federal Ministry of Research, Technology and Space (BMFTR).

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