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Molderings GJ, Kolck UW, Scheurlen C, Brüss M, Homann J, von Kügelgen I (2007) Multiple novel alterations in Kit tyrosine kinase in patients with gastrointestinally
pronounced systemic mast cell activation disorder. Scandinavian Journal of
Gastroenterology 42:1045-1053. PubMed
Molderings GJ, Bönisch H, Brüss M, Wolf C, von Kügelgen I, Göthert M (2007) S1P-receptors in PC12 and transfected HEK293 cells: Molecular targets of hypotensive imidazoline I(1) receptor ligands. Neurochemistry International 2007 May 7 [Epub].
PubMed
Kolck UW, Alfter K, Homann
J, von Kügelgen I, Molderings
GJ (2007) Cardiac mast cells: implications for heart failure. Journal of the
Wolf C, Brüss M, Hänisch
B, Göthert M, von Kügelgen
I, Molderings GJ (2007) Molecular basis for the antiproliferative effect of agmatine
in tumor cells of colonic, hepatic, and neuronal
origin. Molecular Pharmacology 71:276-283. Epub 2006
Oct 17. PubMed
von Kügelgen I (2006) Excitatory P2-receptors at
sympathetic axon terminals: role in temperature control of cutaneous
blood flow. British Journal of Pharmacology 148:561-562. Epub
2006 May 15. PubMed
von Kügelgen I (2006) Pharmacological profiles of
cloned mammalian P2Y-receptor subtypes. Pharmacology & Therapeutics
110:415-432. Epub 2005 Oct 28. PubMed
von Kügelgen I, Algaier I, Di Pasquale F, Hoffmann K, Strassburger
J, Zielinski U (2007) Molecular pharmacology of P2Y(12)-receptors.
Pharmacological reports 58:260-262.
Gorzalka S, Vittori S, Volpini R, Cristalli G, von Kügelgen I, Müller CE. Evidence for the functional expression and pharmacological
characterization of adenine receptors in native cells and tissues.
Molecular Pharmacology 67:955-964. Epub 2004 Dec 16. PubMed
Mamedova LK, Joshi BV, Gao
ZG, von Kugelgen I, Jacobson KA (2004). Diisothiocyanate
derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.
Biochemical Pharmacology 67:1763-1770. PubMed
Vonend O, Grote T, Oberhauser V, von Kügelgen I,
Rump LC (2003) P2Y-receptors stimulating the proliferation of human mesangial cells through the MAPK(42/44)
pathway. Britisch Journal of Pharmacology
139:1119-1126. PubMed
Guo D, von Kügelgen I, Moro S, Kim YC, Jacobson
KA (2002) Evidence for the recognition of non-nucleotide antagonists within the
transmembrane domains of the human P2Y1-receptor.
Drug Development Research 57:173-181.
Vonend O, Oberhauser V, von Kügelgen I, Apel TW, Amann K, Ritz E, Rump LC (2002) ATP release in human kidney
cortex and its mitogenic effects in visceral glomerular epithelial cells. Kidney International
61:1617-1626. PubMed
von Kügelgen I, Wetter A (2000) Molecular
pharmacology of P2Y-receptors. Naunyn-Schmiedeberg's
Archives of Pharmacology 362:310-323. PubMed
Nörenberg W, von Kügelgen I, Meyer A,
Illes P, Starke K (2000) M-type K+ currents in rat
cultured thoracolumbar sympathetic neurones and their
role in uracil nucleotide-induced noradrenaline
release. British Journal of Pharmacology 129:709-723. PubMed
von Kügelgen I, Nörenberg
W, Meyer A, Illes P, Starke K (1999) Role of action
potentials and calcium influx in ATP- and UDP-induced noradrenaline
release from rat cultured sympathetic neurones. Naunyn-Schmiedeberg's
Archives of Pharmacology 359:360-369. PubMed
Queiroz G, Meyer DK, Meyer A, Starke K, von Kügelgen I (1999) A study of the mechanism of the release
of ATP from rat cortical astroglial cells evoked by
activation of glutamate receptors. Neuroscience 91:1171-1181. PubMed
Rump LC, Javad JT, von Kügelgen I, Oberhauser V (1999) Adenosine mediates
nitric-oxide-independent renal vasodilation by
activation of A2A receptors. Journal of Hypertension 17:1987-1993. PubMed
Jacobson
KA, Hoffmann C, Kim YC, Camaioni E, Nandanan E, Yang SY, Guo DP, Ji XD, von Kügelgen I, Moro S, Ziganshin AU, Rychkov A, King BF,
Brown SG, Wildman SS, Burnstock G, Boyer JL, Mohanram A, Harden TK (1999) Molecular recognition in P2
receptors: ligand development aided by molecular modeling and mutagenesis. In: Illes
P, Zimmermann H (Eds.) Nucleotides and their Receptors in the Nervous System. Progress in Brain Research 120. Elsevier; 119-132. PubMed
von Kügelgen I, Nörenberg W, Koch H,
Meyer A, Illes P, Starke K (1999) P2-Receptors
controlling neurotransmitter release from postganglionic sympathetic neurones.
In: Illes P, Zimmermann H (Eds.) Nucleotides and
their Receptors in the Nervous System. Progress in Brain
Research 120. Elsevier; 173-182. PubMed
Nörenberg W, von Kügelgen I, Meyer A,
Illes P (1999) Electrophysiological analysis of
P2-receptor mechanisms in sympathetic neurones. In: Illes
P, Zimmermann H (Eds.) Nucleotides and their Receptors in the Nervous System. Progress in Brain Research 120. Elsevier; 209-221. PubMed
Kittner H, Krügel U, Poelchen W, Sieler D, Reinhardt
R, von Kügelgen I, Illes P
(1999) P2 receptor-mediated activation of noradrenergic and dopaminergic
neurons in the rat brain. In: Illes P, Zimmermann H
(Eds.) Nucleotides and their Receptors in the Nervous System. Progress in Brain Research 120. Elsevier; 223-235. PubMed
Koch H,
von Kügelgen I, Starke K (1998) P2-Receptor-mediated
inhibition of noradrenaline release in the rat
pancreas. Naunyn-Schmiedeberg's Archives of
Pharmacology 357:431-440. PubMed
Rump LC, Oberhauser V, von Kügelgen
I (1998) Purinoceptors mediate renal vasodilation by nitric oxide dependent and independent
mechanisms. Kidney International 54:473-481. PubMed
von Kügelgen I, Gonçalves J, Driessen B, Starke K (1998) Corelease
of noradrenaline and adenosine triphosphate
from sympathetic neurones. Advances in Pharmacology 42:120-125. PubMed
von Kügelgen I (1998) P2-Receptors controlling
the function of postganglionic sympathetic neurones. Pharmacology &
Toxicology 83 Supplement I:73-75
von Kügelgen I, Koch H, Starke K (1997)
P2-Receptor-mediated inhibition of serotonin release in the rat brain cortex. Neuropharmacology 36:1221-1227. PubMed
von Kügelgen I, Nörenberg W, Illes P, Schobert A, Starke K
(1997) Differences in the mode of stimulation of cultured rat sympathetic
neurons between ATP and UDP. Neuroscience 78:935-941. PubMed
Queiroz G, Gebicke-Haerter PJ, Schobert A, Starke K, von Kügelgen
I (1997) Release of ATP from cultured rat astrocytes
elicited by glutamate receptor activation. Neuroscience 78:1203-1208. PubMed
Koch H,
von Kügelgen I, Starke K (1997) P2-Receptor-mediated
inhibition of noradrenaline release in the rat
hippocampus. Naunyn-Schmiedeberg's Archives of
Pharmacology 355:707-715. PubMed
Bohmann C, von Kügelgen I, Rump LC
(1997) P2-Receptor modulation of noradrenergic neurotransmission in rat kidney.
British Journal of Pharmacology 121:1255-1262. PubMed
Silinsky EM, von Kügelgen I, Smith
A, Westfall D (1997) Functions of extracellular
nucleotides in peripheral and central neuronal tissues. In: Turner JT, Weisman
GA, Fedan JS (Eds.) The P2
Nucleotide Receptors. Humana, Totowa; 259-290.
Starke K,
von Kügelgen I, Driessen B,
Bültmann R (1996) ATP release and its prejunctional modulation. In: Chadwick DJ, Goode JA (Eds.)
P2 Purinoceptors: Localization, function and
transduction mechanisms. Ciba Foundation Symposium 198.
John Wiley & Sons,
Rump LC, Bohmann C, Schwertfeger E, Krumme B, von Kügelgen I, Schollmeyer P (1996) Extracellular
ATP in the human kidney: mode of release and vascular effects. Journal of
Autonomic Pharmacology 16:371-375. PubMed
von Kügelgen I, Stoffel
D, Schobert A, Starke K (1996) P2-Purinoceptors on
postganglionic sympathetic neurones. Journal of Autonomic Pharmacology
16:413-416. PubMed
von Kügelgen I (1996) Modulation of neural ATP
release through presynaptic receptors. Seminars in
the Neurosciences 8:247-257.
von Kügelgen I, Stoffel
D, Starke K (1995) P2-purinoceptor-mediated inhibition of noradrenaline
release in rat atria. British Journal of Pharmacology 115:247-254. PubMed
Bohmann C, Rump LC, Schaible U, von Kügelgen I (1995) Alpha-adrenoceptor modulation of norepinephrine
and ATP release in isolated kidneys of spontaneously hypertensive rats.
Hypertension 25:1224-1231. PubMed
Allgaier C, Wellmann H, Schobert A, von Kügelgen I (1995)
Cultured chick sympathetic neurons: modulation of electrically evoked noradrenaline release by P2-purinoceptors. Naunyn-Schmiedeberg's Archives of Pharmacology 352:17-24. PubMed
Allgaier C, Wellmann H, Schobert A, Kurz G, von Kügelgen I (1995) Cultured chick sympathetic neurons: ATP-induced
noradrenaline release and its blockade by nicotinic
receptor antagonists. Naunyn-Schmiedeberg's Archives
of Pharmacology 352:25-30. PubMed
Gonçalves J, Driessen B, von Kügelgen I, Starke K (1995) Comparison of corelease of noradrenaline and
ATP evoked by hypogastric nerve stimulation and field
stimulation in guinea-pig vas deferens. Naunyn-Schmiedeberg's
Archives of Pharmacology 352:229-235. PubMed
von Kügelgen I, Krumme B, Schaible U, Schollmeyer PJ, Rump
LC (1995) Vasoconstrictor responses to the P2X-purinoceptor agonist b,g-methylene-L-ATP in human cutaneous
and renal blood vessels. British Journal of Pharmacology 116:1932-1936. PubMed
von Kügelgen I, Starke K (1995) Kainate receptors are involved in the glutamate-induced
indirect, purinergic inhibition of [3H]-noradrenaline release in rabbit brain cortex. Naunyn-Schmiedeberg's Archives of Pharmacology 353:46-54. PubMed
Rump LC, von Kügelgen I (1994) A study of ATP as a
sympathetic cotransmitter in human saphenous vein. British Journal of Pharmacology 111:65-72. PubMed
von Kügelgen I, Kurz K,
Starke K (1994) P2-purinoceptor-mediated autoinhibition
of sympathetic transmitter release in mouse and rat vas deferens. Naunyn-Schmiedeberg's Archives of Pharmacology 349:125-132.
PubMed
Allgaier C, Pullmann F, Schobert A, von Kügelgen I, Hertting G (1994) P2 purinoceptors
modulating noradrenaline release from sympathetic
neurons in culture. European Journal of Pharmacology 252:R7-R8. PubMed
Driessen B, von Kügelgen I, Starke K
(1994) P1-purinoceptor-mediated modulation of neural noradrenaline
and ATP release in guinea-pig vas deferens. Naunyn-Schmiedeberg's
Archives of Pharmacology 350:42-48. PubMed
von Kügelgen I, Allgaier
C, Schobert A, Starke K (1994) Co-release of noradrenaline and ATP from cultured sympathetic neurons.
Neuroscience 61:199-202. PubMed
von Kügelgen I, Starke K (1994) Corelease of noradrenaline and
ATP by brief pulse trains in guinea-pig vas deferens. Naunyn-Schmiedeberg's
Archives of Pharmacology 350:123-129. PubMed
von Kügelgen I, Späth
L, Starke K (1994) Evidence for P2-purinoceptor-mediated inhibition of noradrenaline release in rat brain cortex. British Journal
of Pharmacology 113:815-822. PubMed
Uri A, Järlebark L, von Kügelgen I, Schönberg T, Unden A, Heilbronn E (1994) A new class of compounds, peptide
derivatives of adenosine 5'-carboxylic acid, includes inhibitors of ATP receptor-mediated
responses. Bioorganic & medicinal chemistry 2:1099-1105. PubMed
Driessen B, von Kügelgen I, Bültmann R, Elrick DB, Cunnane TC, Starke K (1994) The fade of the purinergic neurogenic contraction
of the guinea-pig vas deferens: analysis of possible mechanisms. Naunyn-Schmiedeberg's Archives of Pharmacology 350:482-490.
PubMed
Kurz AK, Bültmann R, Driessen
B, von Kügelgen I, Starke K (1994) Release of ATP in
rat vas deferens: origin and role of calcium. Naunyn-Schmiedeberg's
Archives of Pharmacology 350:491-498. PubMed
von Kügelgen I (1994) Purinoceptors
modulating the release of noradrenaline. Journal of
Autonomic Pharmacology 14:11-12. PubMed
von Kügelgen I, Kurz K, Bültmann R, Driessen B, Starke K
(1994) Presynaptic modulation of the release of the
co-transmitters noradrenaline and ATP. Fundamental
& Clinical Pharmacology 8:207-213. PubMed
Driessen B, Bültmann R, von Kügelgen I, Starke K (1993) Effect of opioid
receptor subtype-selective agonists on purinergic and
adrenergic components of neurogenic contractions of
mouse vas deferens. British Journal of Pharmacology 108:443-447. PubMed
Bültmann R, von Kügelgen I, Starke K
(1993) Effects of nifedipine and ryanodine
on adrenergic neurogenic contractions of rat vas
deferens: evidence for a pulse-to-pulse change in Ca2+ sources. British Journal
of Pharmacology 108:1062-1070. PubMed
von Kügelgen I, Kurz K,
Starke K (1993) Axon terminal P2-purinoceptors in feedback control of
sympathetic transmitter release. Neuroscience 56:263-267. PubMed
Driessen B, von Kügelgen I, Starke K
(1993) Neural ATP release and its alpha2-adrenoceptor-mediated modulation in
guinea-pig vas deferens. Naunyn-Schmiedeberg's
Archives of Pharmacology 348:358-366. PubMed
Kurz K, von Kügelgen I, Starke K (1993) Prejunctional modulation of noradrenaline
release in mouse and rat vas deferens: contribution of P1- and
P2-purinoceptors. British Journal of Pharmacology 110:1465-1472. PubMed
von Kügelgen I, Späth L, Starke K
(1993) Ionotropic glutamate receptor types leading to
adenosine-mediated inhibition of electrically evoked [3H]-noradrenaline
release in rabbit brain cortex slices. British
Journal of Pharmacology 110:1544-1550. PubMed
von Kügelgen I, Starke K (1993) Kotransmission bei der neurogenen
Vasokonstriktion. Phlebologie 22:209-213.
von Kügelgen I, Späth
L, Starke K (1992) Stable adenine nucleotides inhibit [3H]-noradrenaline
release in rabbit brain cortex slices by direct action at presynaptic
adenosine A1-receptors. Naunyn-Schmiedeberg's
Archives of Pharmacology 346:187-196. PubMed
von Kügelgen I, Späth
L, Starke K (1992) Adenosine but not an adenine nucleotide mediates tonic purinergic inhibition, as well as inhibition by glutamate,
of noradrenaline release in rabbit brain cortex
slices. Naunyn-Schmiedeberg's Archives of
Pharmacology 346:677-684. PubMed
Starke K,
von Kügelgen I, Bültmann R
(1992) Noradrenaline-ATP cotransmission:
Operation in blood vessels and cotransmitter release
ratios. Japanese Journal of Pharmacology 58 Suppl. II:166P-173P. PubMed
von Kügelgen I, Starke K (1991) Release of noradrenaline and ATP by electrical stimulation and
nicotine in guinea-pig vas deferens. Naunyn-Schmiedeberg's
Archives of Pharmacology 344:419-429. PubMed
von Kügelgen I, Starke K (1991) Noradrenaline-ATP co-transmission in the sympathetic
nervous system. Trends in Pharmacological Sciences 12:319-324. PubMed
Bültmann R, von Kügelgen I, Starke K (1991) Adrenergic and purinergic cotransmission in nicotine-evoked
vasoconstriction in rabbit ileocolic arteries. Naunyn-Schmiedeberg's Archives of Pharmacology 344:174-182.
PubMed
Bültmann R, von Kügelgen I, Starke K (1991) Contraction-mediating
alpha2-adrenoceptors in the mouse vas deferens. Naunyn-Schmiedeberg's
Archives of Pharmacology 343:623-632. PubMed
Starke K,
von Kügelgen I, Bulloch JM,
Illes P (1991) Nucleotides as cotransmitters
in vascular sympathetic neuroeffector transmission.
Blood Vessels 28:19-26. PubMed
Starke K, von Kügelgen I, Bültmann
R (1991) Prejunctional autoreceptors
in mouse vas deferens. In: Langer SZ, Galzin AM, Costentin J (Eds.) Presynaptic
receptors and neuronal transporters. Advances in the
Biosciences 82. Pergamon Press,
Starke K,
Bültmann R, Bulloch JM, von
Kügelgen I (1991) Noradrenaline-ATP
corelease and cotransmission
following activation of nicotine receptors at postganglionic sympathetic axons.
Journal of Neural Transmission Suppl. 34:93-98. PubMed
von Kügelgen I, Starke K (1990) Evidence for two
separate vasoconstriction-mediating nucleotide receptors, both distinct from
the P2X-receptor, in rabbit basilar artery: a receptor for pyrimidine
nucleotides and a receptor for purine nucleotides. Naunyn-Schmiedeberg's Archives of Pharmacology 341:538-546.
PubMed
von Kügelgen I, Bültmann
R, Starke K (1990) Interaction of adenine nucleotides, UTP and suramin in mouse vas deferens: suramin-sensitive
and suramin-insensitive components in the contractile
effect of ATP. Naunyn-Schmiedeberg's Archives of
Pharmacology 342:198-205. PubMed
von Kügelgen I, Schöffel
E, Starke K (1989) Inhibition by nucleotides acting at presynaptic
P2-receptors of sympathetic neuro-effector transmission
in the mouse isolated vas deferens. Naunyn-Schmiedeberg's
Archives of Pharmacology 340:522-532. PubMed
von Kügelgen I, Bültmann
R, Starke K (1989) Effects of suramin and alpha,beta-methylene-ATP indicate noradrenaline-ATP
co-transmission in the response of the mouse vas deferens to single and low
frequency pulses. Naunyn-Schmiedeberg's Archives of
Pharmacology 340:760-763. PubMed
von Kügelgen I, Häussinger
D, Starke K (1987) Evidence for a vasoconstriction-mediating receptor for UTP,
distinct from the P2 purinoceptor, in rabbit ear
artery. Naunyn-Schmiedeberg's Archives of
Pharmacology 336:556-560. PubMed
Starke K,
Illes P, Ramme D, Ensinger H, Hedler L, Szabo B, von Kügelgen
I, Pfeiffer N, Limberger N (1987) Peripheral pre-junctional opioid receptors in cardivascular control. In: Nobin
A, Owman C, Arneklo-Nobin B
(Eds.) Neuronal Messengers in Vascular Function. Elsevier,
Starke K,
von Kügelgen I, Regenold
JT, Illes P (1987) Presynaptic
alpha2-autoinhibition in vascular neuroeffector
junctions in which noradrenaline and ATP are
co-transmitters. In: Rand MJ, Raper C (Eds.)
Pharmacology. Excerpta medica,
von Kügelgen I, Starke K (1985) Noradrenaline and adenosine-triphosphate
as co-transmitters of neurogenic vasoconstriction in
rabbit mesenteric artery. Journal of Physiology-London 367:435-455. PubMed
Illes P, Pfeiffer N, von Kügelgen
I, Starke K (1985) Presynaptic opioid
receptor subtypes in the rabbit ear artery. Journal of Pharmacology and
Experimental Therapeutics 232:526-533. PubMed
von Kügelgen I, Illes P, Wolf D,
Starke K (1985) Presynaptic inhibitory opioid delta- and kappa-receptors in a branch of the rabbit
ileocolic artery. European Journal of Pharmacology
118:97-105. PubMed
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