Laboratory of Professor Ivar von Kügelgen
Professor of Molecular Pharmacology
University of Bonn

 

 

Research topics:

 

 

 

 

 

Molecular pharmacology of P2Y-like receptors

P2Y-receptors are G-protein-coupled receptors (GPCRs) for extracellular nucleotides such as ATP

 

Predicted secondary structure of  the human platelet P2Y12-receptor

This GPCR is involved in ADP-induced platelet aggregation and is the target of the platelet aggregation blockers clopidogrel and prasugrel

 

 

 

 

 

 

P2Y-receptors controlling neuronal cells and mast cells

 

Processes of differentiated PC12-cells cultured in the presence of nerve growth factor and neurotrophin-3

 

 

 

 

 

 

Mast cell activation disorders

 

HMC1 (Human mast cell line) cells stained with a FITC-conjugated antibody against CD117 (c-kit)

 

 

 

 

 

 

 

 

 

Publications in Pubmed

List of Publications

Address: University of Bonn, Department of Pharmacology, Reuterstrasse 2b, D-53113 Bonn, Germany Tel.: +49 228 735445; Fax.: + 49 228 735443; k u g e l g e n @ u n i - b o n n . d e

Medizinische Fakultät/Medical Faculty - Universität Bonn/University of Bonn
Verantwortlich: Ivar v. Kügelgen, e m a i l : k u g e l g e n @ u n i - b o n n . d e . 28. Aug. 2007. ©2007