LiMES - Program Unit Membrane Biology & Lipid Biochemistry
University of Bonn
Publications
[1.]
N. P. Singh, A. Giannis, E. Henk, T. Kolter, K. Sandhoff, R. R. Schmidt, J. Carbohydr. Chem. 1990, 9, 543 - 559.
"Synthesis of 2-Carboxy-substituted Sphingosine Derivatives".
[2.]
A. Giannis, T. Kolter, GIT Fachz. Lab. 1992, 36, 905.
"Synthese von Peptidaldehyden und Peptidmimetica aus D-Glucosamin Hydrochlorid".
[3.]
T. Kolter, A. Klein, A. Giannis, Angew. Chem. 1992, 104, 1394 - 1395; Angew. Chem. Int. Ed.Engl. 1992, 31, 1391 - 1392.
"Konfigurativ stabile Dipeptidaldehyde aus D-Glucosamin Hydrochlorid".
[4.]
A. Giannis, T. Kolter, Angew. Chem., 1993, 105, 1303-1326; Angew. Chem. Int. Ed. Engl. 1993, 32, 1244 - 1267.
"Peptidmimetica für Rezeptorliganden - Entdeckung, Entwicklung und medizinische Perspektiven".
[5.]
T. Kolter, G. van Echten-Deckert, K. Sandhoff, Tetrahedron 1994, 50, 13425 - 13432.
"Synthesis of Sphinganine Analogues modified in the Head Group".
[6.]
T. Kolter, C. Dahl, A. Giannis, Liebigs Ann. Chem. 1995, 625 - 629.
"Synthesis of Substituted Chiral Piperazinones as Building Blocks for Peptidomimetics".
[7.]
K. Sandhoff, T. Kolter, Naturwissenschaften 1995, 82, 403 - 413.
"Glykolipide der Zelloberfläche - Biochemie ihres Abbaus".
[8.]
T. Kolter, K. Sandhoff, Angew. Chem. 1995, 107, 2559 - 2560; Angew. Chem. Int. Ed. Engl. 1995, 34, 2363 - 2364.
"Neue Gehirnlipide mit schlafinduzierender Wirkung".
[9.]
A. Schick, T. Kolter, A. Giannis, K. Sandhoff, Tetrahedron 1995, 51, 11207 - 11218:
"Synthesis of Phosphonate Analogues of Sphinganine-1-phosphate and Sphingosine-1-phosphate".
[10.]
T. Kolter, F. Rübsam, A. Giannis, M. Nieger, Acta Crystallographica 1996, C52, 978 - 980:
"4-tert-Butyloxycarbonyl-6(S)-(hydroxymethyl)-3(S)-(1-methylethyl)piperazin-2-one".
[11.]
K. Sandhoff, T. Kolter, Trends Cell Biol. 1996, 6, 98-103.
"Topology of glycosphingolipid degradation".
[12.]
A. Schick, T. Kolter, A. Giannis, K. Sandhoff, Tetrahedron 1996, 52, 2945-2956.
"Synthesis of Phosphoramide Analogues of Sphinganine-1-phosphate".
[13.]
R. Kase, U. Bierfreund, A. Klein, T. Kolter, S. Ishi, K. Itoh, M. Suzuki, Y. Hashimoto, K. Sandhoff, H. Sakuraba, FEBS Lett. 1996, 393, 74 - 76.
"Only sphingolipid activator protein B (sap-B or saposin B) stimulates the degradation of globotriaosylceramide by recombinant human lysosomal a-galactosidase A in a detergent-free liposomal system".
[14.]
T. Kolter, K. Sandhoff, Chem. Soc. Rev. 1996, 25, 371 - 381.
"Inhibitors of Glycosphingolipid Biosynthesis".
[15.]
K. Sandhoff, T. Kolter, Clinica Chimica Acta 1997, 266, 51 - 61.
"Biochemistry of glycosphingolipid degradation".
[16.]
A. Schick, G. Schwarzmann, T. Kolter, K. Sandhoff, J. Labell. Comp. Radiopharm. 1997, 39, 441 - 451.
"Synthesis of tritium labelled phosphonate analogues of sphinganine-1-phosphate".
[17.]
T. Kolter, K. Sandhoff, Glycobiology 1997, 7, No. 7 vii - x.
"Sialic acids - why always a-linked?"
[18.]
T. Wieder, C. C. Geilen, T. Kolter, F. Sadeghlar, K. Sandhoff, R. Brossmer, P. Ihrig, D. Perry, C. E. Orfanos, Y. A. Hannun, FEBS Lett. 1997, 411, 260 - 264.
"Bcl-2 antagonizes apoptotic cell death induced by two new ceramide analogues".
[19.]
T. Kolter, K. Sandhoff, "Sphingolipidosen" in: D. Ganten, K. Ruckpaul (Hrsg.): Handbuch der Molekularen Medizin, Band 6, Monogen bedingte Erbkrankheiten 1, Kap. 2.3, Springer-Verlag, 2000, S. 195 - 234.
[20.]
T. Kolter, Angew. Chem. 1997, 109, 2044 - 2048; Angew. Chem. Int. Ed. Engl. 1997, 36, 1955 - 1959.
"Ein chemisches Konzept zur Behandlung der Tay-Sachs'schen Erkrankung."
[21.]
K. Sandhoff, T. Kolter, G. van Echten-Deckert, Annals of the New York Academy of Sciences 1998, 845, 139 - 151.
"Sphingolipid Metabolism - Sphingoid analogues, sphingolipid activator proteins and the pathology of the cell".
[22.]
T. Kolter, K. Sandhoff, J. Inher. Metab. Dis. 1998, 21, 548 - 563.
"Glycosphingolipid degradation and animal models of GM2-Gangliosidoses".
[23.]
K. Sandhoff, T. Kolter, Acta Biochimica Polonica 1998, 45, 373 - 384.
"Processing of Sphingolipid Activator Proteins and the Topology of Lysosomal Digestion"
[24.]
T. Kolter, K. Sandhoff, Brain Pathology 1998, 8, 79 - 100.
"Recent advances in the biochemistry of sphingolipidoses."
[25.]
M. Bektas, Y. Dullin, T Wieder, T. Kolter, K. Sandhoff, R. Brossmer, P. Ihrig, C. E. Orfanos, C. C. Geilen, Exp. Dermatol. 1998, 7, 342 - 349.
"Induction of apoptosis by synthetic ceramide analogues in the human keratinocyte cell line HaCaT"
[26.]
K. Sandhoff, T. Kolter, K. Harzer, Sphingolipid Activator Proteins in:
"The Metabolic and Molecular Bases of Inherited Disease, 8th Edition, Vol. III, 3371 – 3389 (2001).
[27.]
T. Kolter, K. Sandhoff, Angew. Chem. 1999, 111, 1633 - 1670; Angew. Chem. Int. Ed. 1999, 38, 1532 - 1568.
"Sphingolipide - ihre Stoffwechselwege und die Pathobiochemie neurodegenerativer Erkrankungen"
[28.]
T. Kolter, K. Sandhoff, Trends Glycosci. Glycotechnol. 1998, 10, 455 - 468.
"Enzymology of lysosomal glycolipid catabolism"
[29.]
F. K. Knoll, T. Kolter, K. Sandhoff, Methods in Enzymology 1999, 311, 568 - 600.
"Sphingolipid photoaffinity labels"
[30.]
U. Bierfreund, T. Kolter, K. Sandhoff, Methods in Enzymology 1999, 311, 255 - 276.
"Sphingolipid hydrolases and activator proteins"
[31.]
T. Kolter, K. Sandhoff, in: B. Fraser-Reid, K Tatsuta, J. Thiem (Hrsg.): Glycoscience: Chemistry and Chemical Biology III, Chapter 7.4, 2149 – 2182, Springer, Berlin, 2001.
"Animal Glycolipids: Biosynthesis and degradation".
[32.]
G. Uhlhorn-Dierks, T. Kolter, K. Sandhoff, Angew. Chem. 1998, 110, 2591 - 2594; Angew. Chem. Int. Ed. Engl. 1998, 37, 2453 - 2455.
"Wie werden Schwefelsäureester in der Natur gespalten? Eine neuartige posttranslationale Modifikation bei Sulfatasen"
[33.]
T. Kolter, K. Sandhoff in: B. Ernst, G. Hart, P. Sinay (Hrsg.), Oligosaccharides in Chemsitry and Biology: A comprehensive handbook, Vol. 3, Part II: Glycosidases, 455 – 472.
"Lysosomal degradation of glycolipids."
[34.]
M. Wendeler, T. Kolter, K. Sandhoff, Neuroscientist 2000, 6, 285 – 296.
"Pathology of sphingolipid metabolism, the molecular and cellular basis of neurodegenerative diseases."
[35.]
C. G. Schuette, T. Döring, T. Kolter, K. Sandhoff, Biospektrum 1999, 5, 365 - 370.
"Die Glykosphingolipidosen - von Krankheiten zu Prinzipien des Stoffwechsels".
[36.]
T. Kolter, T. Döring, G. Wilkening, N. Werth, K. Sandhoff, Biochem. Soc. Trans. 1999, 409 - 415.
"Recent advances in the biochemistry of Glycosphingolipid metabolism".
[37.]
A. Huwiler, T. Kolter, J. Pfeilschifter, K. Sandhoff, Biochim. Biophys. Acta 2000, 1485, 63 – 99.
"Physiology and pathophysiology of sphingolipid metabolism and signaling".
[38.]
R. Kase, U. Bierfreund, A. Klein, T. Kolter, K. Utsumi, K. Itoh, K. Sandhoff, H. Sakuraba, Biochim. Biophys. Acta 2000, 1501, 227 – 235.
"Characterization of two a-galactosidase mutants (Q279E and R301Q) found in an atypical variant of Fabry disease".
[39.]
C. G. Schuette, T. Doering, T. Kolter, K. Sandhoff, Biol. Chem. 1999, 380, 759 - 766.
"The Glycosphingolipidoses - from Disease to basic principles of metabolism".
[40.]
M. Wendeler, T. Kolter, Chemie in unserer Zeit 1999, 33, 368 – 370.
"Die Transportlogistik der Zelle - Günter Blobels Signalhypothese".
[41.]
U. H. Schueler, T. Kolter, C. R. Kaneski, J. K. Blusztaj, M. Herkenham, K. Sandhoff, R. O. Brady, Neurobiology of Disease 2003, 14, 595 – 601.
"Toxicity of glucosylsphingosine (glucopsychosine) to cultured neuronal cells: a model system for assessing neuronal damage in Gaucher disease type 2 and 3."
[42.]
T. Kolter, T. Magin, K. Sandhoff, Traffic 2000, 1, 803 – 804.
"Biomolecule function: no reliable prediction from cell culture".
[43.]
U. Schepers, T. Kolter, Angew. Chem. 2001, 113, 2503 - 2505; Angew. Chem. Int. Ed.. 2001, 40, 2437 - 2439.
"RNA Interferenz: ein neuer Weg zur Proteinfunktion".
[44.]
O. Macheleidt, T. Kolter, K. Sandhoff in: F. Platt, S. U. Walkley, Lysosomal disorders of the brain. Chapter 8:
"Sphingolipid activator deficiencies and Niemann-Pick Type C".
[45.]
T. Kolter, R. L. Proia, K. Sandhoff, J. Biol. Chem. 2002, 277, 25859-25862.
Minireview: "Combinatorial ganglioside biosynthesis."
[46.]
M. Wendeler, H. Reilaender, J. Hoernschemeyer, G. Schwarzmann, T. Kolter, K. Sandhoff in: Y. C. Lee, R. T. Lee (Eds.), Methods in Enzymology 2003, 363, 476 - 489.
"Recombinant Ganglioside GM2-Synthase – Expression in Insect Cells and Enzyme Assay".
[47.]
P. Sawatzki, T. Mikeska, M. Nieger, H. Hupfer, T. Kolter, Acta Cryst. 2002, E58, o359-o361.
"tert-Butyl 4-acetyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate".
[48.]
T. Kolter in C. Schmuck, H. Wennemers (Hrsg.): Bioorganic Chemistry II, Wiley-VCh.
"Conformational restriction of sphingolipids".
[49.]
S. Brodesser, P. Sawatzki, T. Kolter, Eur. J. Org. Chem. 2003, 2021 – 2034.
"Bioorganic Chemistry of Ceramide".
[50.]
P. Sawatzki, M. Skowron, G. van Echten-Deckert, T. Kolter, Bioorg. Med. Chem. Lett., eingereicht.
"Ceramide Analogs with bioisosteric replacements".
[51.]
K. Sandhoff, T. Kolter, Philos. Trans. R. Soc. Lond. B Biol. Sci. 358, 847-861.
"Biosynthesis and degradation of mammalian glycosphingolipids".
[52.]
P. Sawatzki, T. Mikeska, M. Nieger, H. Hupfer, T. Kolter, Acta Cryst. 2002, E58, o1415-o1417.
"2(S)-N-tert.-Butoxycarbonylamino-N-methoxy-N-methyl-butanamide"
[53.]
P. Sawatzki, T. Mikeska, K. Sandhoff, M. Nieger, T. Kolter, Acta Cryst. 2003, E59, o171-o173.
"6(S)-Methyl-3(S)-methylethyl-piperazin-2-one."
[54.]
T. Kolter, M. Wendeler, ChemBioChem 2003, 4, 260-264.
"Minireview: Chemical Chaperones – a new concept in drug research."
[55.]
P. Sawatzki, T. Mikeska, M. Nieger, M. Bolte, T. Kolter, Acta Cryst. 2003, C59, o225-o227.
"(4S,5S)-4-[(1R)-1,2-Dihydroxyethyl]-5-tridecyl-1,3-oxazolidin-2-one."
(dazu: Issue cover und Kommentar in IUCr Newsletter)
[56.]
M. Wendeler, T. Kolter, Angew. Chem. 2003, 115, 3044 - 3047.
"Highlight: Das Endocannabinoid-System als Target neuer Wirkstoffe."
[57.]
T. Kolter, "Glycosphingolipids". In: A. Nicolaou, G. Kokotos (Hrsg.): Bioactive Lipids. Chapter 7, pp. 169 - 196. The Oily Press 2004, P. J.
Barnes & Associates, Bridgwater, UK.
[58.]
T. Kolter, K. Sandhoff, "Lysosomal sphingolipid storage diseases." In: M. Fukuda, U. Rutihauser, R. Schnaar, Y. Yamaguchi,
Neuroglycobiology. Oxford University Press, Oxford, 2005.
[59.]
T. Mikeska, M. Nieger, H. Mansikkamäki, J. Daniels, T. Kolter, Carbohydr. Res. 2003, 338, 2119 – 2128.
"Crystal structures of O-acetylated 2-acylamino-2-deoxy-D-galactose derivatives."
[60.]
S. Brodesser, T. Mikeska, M. Nieger, T. Kolter, Acta Cryst.2003, E59, o1359 - o1361.
"1,1-Dimethylethyl N-propanoylcarbamate."
[61.]
U. H. Schueler, T. Kolter, C. R. Kaneski, G. C. Zirzow, K. Sandhoff, R. O. Brady, J. Inher. Metab. Dis., 2004, 27, 649-658.
"Correlation between Enzyme activity and Substrate Storage in a Cell Culture Model System for Gaucher disease."
[62.]
T. Kolter, ChemBioChem 2003, 4, 1303 – 1305.
"Sticky proteins for Stem cells. Highlight."
[63.]
M. Wendeler, J. Hoernschemeyer, D. Hoffmann, T. Kolter, G. Schwarzmann, K. Sandhoff, Eur. J. Biochem. 2004, 271, 614 - 627.
"Photoaffinity Labeling of Human GM2-Activator Protein - Mechanistic Insight into Ganglioside GM2 Degradation."
[64.]
P. Sawatzki, T. Kolter, Eur. J. Org. Chem. 2004, 3693 - 3700.
"Synthesis of 3-C-Methyl-ceramides."
[65.]
P. Sawatzki, I. Damm, B. Pierstorff, H. Hupfer, K. Sandhoff, T. Kolter, ChemBioChem 2005, 6, 178-185:
"Site-specific cleavage – a model system for the identification of lipid-modified glutamate residues in proteins."
[66.]
M. Wendeler, J. Wirtz, T. Kolter, Drug Design Reviews - Online 2005, 2, 53 - 65.
"Sphingolipids as emerging drug targets."
[67.]
S. Locatelli Hoops, T. Kolter, K. Sandhoff, in: A. H. Futerman, A. Zimran, Gaucher Disease, Taylor & Francis, Boca Raton, 2007, 67-84.
"Saposin C and other sphingolipid activator proteins"
[68.]
T. Kolter, K. Sandhoff, Annu. Rev. Cell Dev. Biol. 2005, 21, 81–103.
"Principles of lysosomal membrane digestion – Stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids."
[69.]
T. Kolter, F. Winau, U. E. Schaible, M. Leippe, K. Sandhoff, J. Biol. Chem. 2005, 280, 41125-41128.
"Lipid binding proteins in membrane digestion, antigen presentation and antimicrobial defense."
[70.]
T. Kolter, K. Sandhoff, Biochim. Biophys. Acta 2006, 1758, 2057-79.
"Sphingolipid Metabolism Diseases."
[71.]
Megha, P. Sawatzki, T. Kolter, R. Bitman, E. London, Biochim. Biophys. Acta 2007, 1768, 2205-12.
"Effect of ceramide acyl chain and polar headgroup structure on the properties of ordered lipid domains (lipid rafts)."
[72.]
A. Dommisse, J. Wirtz, K. Koch, W. Barthlott, T. Kolter, Eur. J. Org. Chem. 2007, 3508 - 3511.
"Synthesis of (S)-Nonacosan-10-ol, the Major Component of Tubular Plant
Wax Crystals."
[73.]
M. Wendeler, N. Werth, T. Maier, G. Schwarzmann, T. Kolter, M. Schoeninger, D. Hoffmann, T. Lemm, W. Saenger, K. Sandhoff, FEBS J. 2006, 273, 982-91.
"The enzyme-binding region of human GM2-activator protein"
[74.]
H. Farwanah, T. Kolter, Wiley Encyclopedia of Chemical Biology (online-Artikel), .
"Lipidomics."
[75.]
H. Farwanah, B. Pierstorff, C. E. H. Schmelzer, K. Raith, R. H. H. Neubert, T. Kolter, K. Sandhoff,
J. Chromatography B, Analyt. Technol. Biomed. Life Sci. 2007, 852, 562-570:
"Separation and mass spectrometric characterization of covalently bound skin ceramides using LC/APCI-MS and Nano-ESI-MS/MS"
[76.]
J. Wirtz, T. Kolter, ChemBioChem 2007, 24, 1631-5.
"Novel tools for the proteomic identification of acylated proteins"(Highlight)
[77.]
T. Kolter, Angew. Chem. 2007, 119, 6895-6898 / Angew. Chem. Int. Ed. 2007, 46, 6772-5.
"Die Fettsäurefabrik der Hefe"/(Highlight)
[78.]
N. Robinson, T. Kolter, M. Wolke, J. Rybniker, P. Hartmann, G. Plum, Traffic 2008, 9, 1936-47.
"Mycobacterial phenolic glycolipid inhibits phagosome maturation and subverts pro-inflammatory cytokine response"
[79.]
H. Schulze, T. Kolter, K. Sandhoff, Biochim. Biophys. Acta 2009, 1793, 674-83.
"Principles of lysosomal membrane degradation Cellular topology and biochemistry of lysosomal lipid degradation"
[80.]
H. Farwanah, J. Wirtz, T. Kolter, K. Raith, R. H. H. Neubert, K. Sandhoff, J Chromatogr B Analyt Technol Biomed Life Sci. 2009, 877; 2976-82.
"Normal phase liquid chromatography coupled to quadrupole time of flight atmospheric pressure chemical ionization mass spectrometry for separation, detection and mass spectrometric profiling of neutral sphingolipids and cholesterol."
[81.]
T. Kolter, K. Sandhoff, FEBS Lett. 2010, 584, 1700-12.:
"Lysosomal Degradation of Membrane Lipids."
[82.]
S. Brodesser, T. Kolter, J. Lipids, Volume 2011 Article ID 724015 (doi:10.1155/2011/724015):
"Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes."
[83.]
T. Kolter, Chem. Phys. Lipids 2011, 164, 590-606.
"A view on sphingolipids and disease"
[84.]
H. Farwanah, T. Kolter, K. Sandhoff, Biochim Biophys Acta. 2011, 1811, 854-60. "Mass spectrometric analysis of neutral sphingolipids:
Methods, applications, and limitations"
[85.]
S. Locatelli Hoops, T. Kolter, K. Sandhoff, in: Lajtha, A. (Ed.), Handbook of Neurochemistry and Molecular Neurobiology - Neural Lipids, 3rd Ed., Springer, 2009, 671-701.
"Sphingolipid-Inherited Diseases of the Central Nervous System"
[86.] H. Farwanah, T. Kolter, Metabolites 2012, 2, 134-164. "Lipidomics of Glycosphingolipids."
"Roempp-Online:" Bearbeitung der Themenbereiche
"Lipide, Steroide, Isoprenoide, Fettstoffwechsel"
"Enzyme, Coenzyme, Porphyrine"
"Vitamine, Hormone"
"Pharmazeutische Wirkstoffe"
Manuscripts in press
T. Kolter in G.C.K. Roberts (Ed.), Encyclopedia of Biophysics (Springer). "Lipidomics"
T. Kolter in G.C.K. Roberts (Ed.), Encyclopedia of Biophysics (Springer). "Sphingolipids and Gangliosides"
Rezensionen
